![]() The cover shows the pangenome wrapping a globe and uses a sequence tube map rendering of a pangenome graph relating ten haplotypes within the highly variable HLA-A locus on chromosome 6 created by Adam Novak at the University of California, Santa Cruz. These results come from an early stage in the pangenome project, which ultimately aims to capture the genetic diversity of at least 350 individuals. Two additional papers use this new resource to study regions of the genome that include repetitive DNA: one looking at segmental duplications, the other at the short arms of acrocentric chromosomes. Books of Blood: Volumes 4-6 Paperback 54 ratings See all formats and editions Hardcover 39.89 13 Used from 4.49 4 New from 36.24 3 Collectible from 50.00 Paperback from 57.90 6 Used from 57.90 3 New from 57.91 Mass Market Paperback 59.99 1 Used from 59. ![]() In this week’s issue, the Human Pangenome Reference Consortium presents the first draft human pangenome, which combines genetic material from 47 genetically diverse individuals to provide a more complete picture of the human genome. But it has its limitations: one genome cannot hope to capture the diversity of the human species. The human reference genome has been the backbone of human genomics since the release of the draft sequence in 2001. ![]()
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